Clue: "O Brother, Where Art __?"; 2000 George Clooney movie

We have 1 answer for the crossword clue "O Brother, Where Art __?"; 2000 George Clooney movie.

Possible Answers:

• THOU

Related Clues:

• Old-style you
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• "How Great ___ Art"
• Thousand (abbr.)
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• "___ Swell" (Rodgers & Hart song)
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• ... and 23 more.

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