Clue: Major nuisance

We have 1 answer for the crossword clue Major nuisance.

Possible Answers:

• PAIN

Related Clues:

• Bodily distress
• Royal annoyance?
• Annoying person
• ___ in the neck
• Cause to grimace
• "No ___, no gain"
• "No __, no gain"
• "Why is my --- perpetual" (Jer 15:18)
• Agony
• Pang
• Ache
• Prerequisite for gain?
• Analgesic target
• (k) Ache
• Neck ailment?
• "No ___, no gain" (gym saying)
• Tylenol target
• No gain without it
• Percocet's target
• Annoyance
• Injury
• Physical discomfort
• (K) What a toothache causes
• Royal problem?
• Boy, does it hurt
• ... and 13 more.

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